Bromocriptine (originally marketed as Parlodel, subsequently under many names) [1] is an ergoline derivative and dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and, as an adjunct, type 2 diabetes.. Our Parlodel (bromocriptine mesylate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Anticholinergics such as bromocriptine can stop severe muscle spasms of the back, neck, and eyes that are sometimes caused by psychiatric drugs. It is usedto treat Parkinson's disease and conditions caused by too much of the hormone, prolactin. Nausea, vomiting, fatigue, headaches, dizziness, and syncope have been observed as side effects in 50–70% of women following oral administration of bromocriptine. In a 52-week safety trial in which all serious adverse events and cardiovascular endpoints were adjudicated, serious adverse events occurred in 8.5% of drug treated patients compared with 9.6% of placebo patients. Constipation. It helps to control blood pressure by relaxing blood vessels. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to bromocriptine: compounding powder, oral capsule, oral tablet, The incidence of adverse reactions with this drug are high, but generally mild to moderate in degree. vitamins, herbal supplements, etc. You may report side effects to FDA at 1-800-FDA-1088. Nausea 11. All drugs may cause side effects. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The composite cardiovascular endpoint occurred in 31 (1.5%) drug-treated patients and 30 (3%) placebo patients. All rights reserved. Perindopril may be used alone or in combination with other medications that reduce blood pressure, especially thiazide diuretics (water pills). Valeant Pharmaceuticals, Costa Mesa, CA. Call your doctor for medical advice about side effects… Most of these side effects are mild and transient if administered at bedtime and/or with food. Estrogen replacement can prevent the effects of estrogen deficiency but it carries the risk of thromboembolism. Sometimes you may need medical treatment if you experience side […] Acta Obstet Gynecol Scand 70 (1991): 375-6, 8. These may include lowered blood pressure with dizziness or light-headedness when getting up quickly, headaches, nausea, fatigue, nasal congestion, constipation, and drowsiness. J Natl Med Assoc 85 (1993): 700-1, 9. Dopamine agonists such as carmoxirole, cabergoline and bromocriptine have been suggested for the management of hyperprolactinemia in patients receiving antipsychotics, but these are associated with side-effects and may worsen psychosis. Document increased side effects such as involuntary movements (dyskinesias) or fluctuations in response (on-off phenomenon, end-of-dose akinesia). Latest prescription information about Bromocriptine. Inflammation Of The Tissue Lining The Sinuses 8. Some side effects of bromocriptine may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Occasionally, bromocriptine can cause some more serious side-effects. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Minor side effects can occur when first starting the medication but usually rapidly improve as your body gets accustomed to it. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. ).Some health conditions may make you more susceptible to the side-effects of the drug. Increased plasma level w/ erythromycin and other macrolide antibiotics. Ann Pharmacother 33 (1999): 1050-4, 6. Learn about side effects, warnings, dosage, and more. There was an improvement in both respiratory and general symptoms, which was more evident in patients surviving more than 95 days. Dizziness 4. The reason(s) for this difference may be explained by one or more mecha­ Bromocriptine is not recommended to prevent unwanted breast milk after pregnancy, miscarriage or abortion, due to potential severe side effects (such as high blood pressure, seizure, heart attack, stroke). Kaushik P, Vatsavai SR, Banda VR, Sanghi PK, Ahmad M, Kaushik R "Acute onset of severe dilated cardiomyopathy during bromocriptine therapy." Bromocriptine should not be used to stop breast milk production in women who have had an abortion or stillbirth or who have chosen not to breast-feed; bromocriptine may cause serious or fatal adverse effects in these women. Bromocriptine can also cause other side effects. Low Energy 10. Commonly reported side effects of bromocriptine include: symptomatic hypotension. This is not a complete list of side effects and others may occur. Leiguarda R, Merello M, Sabe L, Starkstein S "Bromocriptine-induced dystonia in patients with aphasia and hemiparesis." "Product Information. Cycloset (bromocriptine)." "Product Information. Call your doctor for medical advice about side effects. All drugs may cause side effects. Slowly increasing the dose helps with side effects. Constipation. Lopressor (metoprolol tartrate) is a prescription drug that treats high blood pressure, angina, and other conditions. Peter SA, Autz A, Jean-Simon ML "Bromocriptine-induced schizophrenia." You may report them to the FDA. Some side effects may not be reported. This could raise the level of bromocriptine in your body and increase your risk of side effects from bromocriptine. Lancet 340 (1992): 1210-411, 11. Along with its needed effects, bromocriptine may cause some unwanted effects. Bromocriptine systemic 2.5 mg (BCT 2 1/2), We comply with the HONcode standard for trustworthy health information -, Drug class: dopaminergic antiparkinsonism agents, feeling, seeing, or hearing things that are not there, feeling that others are watching you or controlling your behavior, feeling that others can hear your thoughts, inability to move the arms, legs, or facial muscles, pain or discomfort in the arms, jaw, back, or neck, uncontrolled movements of the body, such as the face, tongue, arms, hands, head, and upper body, chest pain, possibly moving to the left arm, neck, or shoulder, false beliefs that cannot be changed by facts, tingling or pain in the fingers and toes when exposed to cold temperatures. Bromocriptine appears to have no harmful effect on hepatic, renal, haematologic, or cardiac functions. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Rare cases of serious adverse events including hypertension, myocardial infarction, seizures, and strokes, have been reported in postpartum women. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. [Ref], Retroperitoneal fibrosis has been reported in a few patients receiving this drug in doses ranging from 30 to 140 mg/day for 2 to 10 years. In the 8-week, double-blind period of the comparative trial with bromocriptine, DOSTINEX (at a dose of 0.5 mg twice weekly) was discontinued because of an adverse event in 4 of 221 patients (2%) while bromocriptine (at a dose of 2.5 mg two times a day) was discontinued in 14 of 231 patients (6%). It may be taken by mouth, rectally, injection into a vein, or injection into a muscle. More common side effects. If you notice any other effects, check with your healthcare professional. This medication guide provides information about the Parlodel brand of bromocriptine. If you stop taking this medicine when it is being used for tumor treatment, the tumor may regrow quickly, and your original symptoms may return. You may report side effects to the FDA at 1-800-FDA-1088. See what others have said about , including the effectiveness, ease of use and side effects. These conditions include some types of menstrual problems, increased milk production, female infertility, male development problems, and small tumours called adenomas. Copyright © 2021 IBM Watson Health. Notify physician because increased side effects might require dose adjustment or a change in medication regimen. This is not a complete list of side effects and others may occur. You may need blood work done while you are taking this medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. pregnancy, upcoming surgery, etc. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Parlodel As with all medicines, patients treated with Parlodel® (bromocriptine mesylate) may have side effects, although not everyone gets them. ( 1992 ): 2319-22, 12 the Cycloset brand of bromocriptine include symptomatic. Interest e-newsletter keeps you up to date on a wide variety of health topics for serious side effects require... 43 ( 1993 ): 2319-22, 12 to treat rheumatoid arthritis and psoriasis Jean-Simon ML Bromocriptine-induced. Rascol O `` Alopecia: an adverse effect of bromocriptine may cause some unwanted.... ( metoprolol tartrate ) is a prescription drug that treats high blood pressure especially! Notice any other effects, a medicine may cause some unwanted effects they may need medical attention healthcare.... 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